Al Ahly registered a hard-fought 1-0 victory over Esperance de Tunis in the 2020/21 Caf Champions League.
The two sides faced of in the semi-final first-leg match on Saturday evening at Stade Olympique de Rades.
Mohamed Sherif’s second-half goal earned the Egyptian champions the win in the Tunisian city of Rades.
Mosimane was hoping to mastermind his first win over Esperance.
He had lost once and drawn once against the Tunisian champions during his time with Mamelodi Sundowns.
Mosimane rewarded Salah Mohsen with a starting berth.
The attacker came off the bench to score in Al Ahly’s 2-0 win over Moroccan outfit RS Berkane in Caf Super Cup.
Al Ahly faced struggling Esperance
Al Ahly were facing an Esperance side that had lost four of their last five competitive matches.
Their most recent game was a 1-0 defeat to Etoile du Sahel in the Tunisian Cup game on May 26.
The first real chance of the game was created by Ali Maaloul, who had been handed his maiden start for the Red Devils since February this year by Mosimane.
The Tunisia international played a quick free-kick to the unmarked Sherif.
His angled effort was blocked by well-positioned goalkeeper Moez Ben Cherifia.
Sherif thought he had handed Al Ahly the lead when he fired home after Ben Cherifia had pushed the ball into his path.
But the goal was disallowed for offside.
However, the Blood and Gold finished the first-half the stronger of the two teams.
Mohamed Ali Ben Romdhane cut inside before unleashing a shot which was brilliantly saved by keeper El Shenawy.
Al Ahly were then able to contain Esperance until referee Victor Gomes blew the half-time whistle.
The two teams continued to create chances after the restart.
Khalid Abdul-Basit forced El Shenawy into an easy save.
Taher Mohamed Taher hit the side-netting at the other end with the Esperance defence exposed.
Mosimane was forced to make a change when Mohsen went down injured.
He was replaced by Mohamed Magdi Kafsha, who helped the Red Devils take full control of the match.
The visitors deservedly took the lead when Sherif scored from a rebound to make it 1-0 to Al Ahly in the 67th minute.
His initial shot had hit the upright following a defence-splitting pass from Aliou Dieng.