This followed their 2-0 win against Mbarara City on Tuesday.
A goal in each half from Brian Majwega and Shafik Kagimu ensured the Tax Collectors picked up their first-ever win over the Ankole Lions.
Their first win came after six attempts at the Arena of Visions in Ndejje.
It was Majwega who put the Sam Ssimbwa-led side into the lead with only ten minutes played.
He stepped up to convert from the penalty spot, sending Mbarara goalkeeper Steve Elungat in the wrong direction.
The Tax Collectors could have added the second in the 34th minute but Kagimu’s header hit the woodwork.
And his effort from the rebound went inches wide.
URA FC went into the half-time break enjoying a 1-0 lead and after the start of the second half.
They continued to pile pressure for more goals and it was no surprise when Kagimu made it 2-0 in the 61st minute.
He slotted home a pass from second-half substitute Ivan Sserubiri.
They could have been 3-0 up three minutes later as Joackiam Ojera whipped a superb ball into the danger zone.
But Ibrahim Dada’s header was deflected out by a Mbarara City defender for a fruitless corner kick.
Despite a late surge by Mbarara to break down URA, the score remained 2-0.
The Tax Collectors picked up their first ever win against the Ankole Lions in the top-flight.
The win enabled URA to stretch their lead at the summit to 47 points, four more than second-placed Vipers SC who have 43 points.